This is the second loss for Madonna's family in a short span. Just last month, her stepmother, Joan Ciccone, also passed away following a fight against aggressive cancer.
Christopher and Madonna shared a close bond in the early days of her career. He was initially one of her backup dancers and later took on roles as her show designer and backstage dresser. His work extended to serving as the art director for Madonna's iconic "Blonde Ambition" world tour. He also directed her tours, including "The Girlie Show," and directed music videos for stars like Tony Bennett and Dolly Parton.
Though the siblings had a public falling out in 2008, after Christopher released his biography, Life With My Sister Madonna, which became a New York Times best seller, they eventually reconciled. In 2012, Christopher ventured into fashion, launching his own footwear line.
Christopher Ciccone was 63 years old.